MEL-18 regulates ESR1 transcription by inhibiting brand new SUMOylation of your ESR1 transcription circumstances p53 and you may SP1
MEL-18 regulates ESR1 transcription by inhibiting brand new SUMOylation of your ESR1 transcription circumstances p53 and you may SP1 (A) Cell lysates treated with 20 mM N-ethylmaleimide (NEM) were subjected to immunoblotting. The amount of SUMOylated protein was quantified by measuring the ratio of SUMOylated protein/total protein. (B) Venn diagram showing the relationship between the …